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Epigenetics of congestive heart failure

Congestive heart failure (CHF) is a worldwide epidemic. It is estimated, for example, that in Europe around 10 million people are suffering [read more]

Genome organization in cardiac remodeling

Transcriptional regulation in mammals was simplistically viewed as a process in which soluble protein factors are recruited to promotersĀ [read more]


Concentric and eccentric hypertrophy

Heart failure can be divided into different pathophysiological and functional categories. A key feature of congestive heart failure isĀ [read more]

Vascular and valve calcification

Most aging individuals have progressively enlarging accumulation of calcium in their major arteries. These vascular calcifications [read more]