Research fields

Signaling in heart failure

Congestive heart failure (CHF) is a worldwide epidemic. It is estimated, for example, that in Europe around 10 million people are suffering [read more]

Genome organization in cardiac remodeling

Transcriptional regulation in mammals was simplistically viewed as a process in which soluble protein factors are recruited to promoters [read more]

Growth and maintenance of the sarcomere

Heart failure is a global problem with an estimated prevalence of 38 million patients worldwide, a number that is increasing  [read more]

Vascular and valve calcification

Most aging individuals have progressively enlarging accumulation of calcium in their major arteries. These vascular calcifications [read more]